Acetaminophen and hydrocodone are a combination medicine used to relieve moderate to severe pain. Acetaminophen and hydrocodone contain an opioid medicine and may be habit-forming.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue-colored lips, or if you are hard to wake up.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have a wasting syndrome or chronic breathing disorders.
Common side effects include:
dizziness, drowsiness, feeling tired;
nausea, vomiting, stomach pain;
Tell your doctor if you have ever had:
breathing problems, sleep apnea (breathing stops during sleep);
a drug or alcohol addiction;
a head injury or seizures;
urination problems; or
problems with your thyroid, pancreas, or gallbladder.